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Creation and integration mechanism of instrumentation flexible developing system
Xiaoli XU, Qiushuang LIU
Frontiers of Mechanical Engineering 2011, Volume 6, Issue 2, Pages 235-240 doi: 10.1007/s11465-011-0122-5
Keywords: modern instrumentation developing flexible interconnection flexible integration mechanism rapid integration
Advances in newly developing therapy for chronic hepatitis C virus infection
Paul J. Pockros
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 166-174 doi: 10.1007/s11684-014-0334-2
Chronic hepatitis C virus (HCV) infection afflicts a reported 170 million people worldwide and is often complicated by cirrhosis and hepatocellular carcinoma. Morbidity and mortality are decreased with the successful treatment of chronic HCV infection. Increased understanding of the HCV has allowed further development of new direct-acting antiviral (DAA) agents against the HCV and has also allowed the development of IFN-free oral treatment regimens. In late 2013 the first nucleotide polymerase inhibitor regimen with RBV alone for genotypes 2/3 and in combination with a 12-week regimen of PEG-IFN+RBV for genotypes 1, 4 was approved for use in the US. A number of promising new DAA regimens which are IFN-free are in phase 3 development and the first will likely be approved for use in the US in 2014. The currently approved regimens are discussed in detail and currently available data on future regimens are reviewed herein.
Keywords: direct-acting antiviral (DAA) nucleotide polymerase inhibitors protease inhibitors
Barriers and countermeasures in developing traditional Chinese medicine in Europe
Yunfang Liu,Zhiping Yang,Jing Cheng,Daiming Fan
Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 360-376 doi: 10.1007/s11684-016-0455-x
Traditional Chinese medicine (TCM) is one of the unique cultural treasures of Chinese; it represents a significant feature and prominent advantage of the healthcare cause in China. Data in this paper were from World Health Organization, Chinese Bureau of Statistics, China National Knowledge Infrastructure, and PubMed. In recent years, TCM has established a solid foundation in Europe, which made great strides in legislation, education, research, and international exchange, and has enjoyed a vast development space in the continent. Now, TCM is embracing unprecedented development opportunities in Europe. At the same time, the stiff international competition poses a grave threat to China’s TCM industry. With multiple cultural, legal, and institutional challenges, as well as talent shortages in the way, TCM is now facing many difficulties in Europe. To fully prepare and enact active and vigorous steps to seize opportunities, we should have a clear picture about the serious challenges hampering TCM development in Europe. The TCM development at overseas markets has shifted from a spontaneous trade activity into a national strategy spearheaded by the government and participated in by multiple stakeholders. We should make a systematic, comprehensive, and sustainable push in fields such as TCM therapy, healthcare, education, research, culture, and industry development. The ultimate goal is to bring TCMs to the global market and allow them to play a role in safeguarding public health along with modern medicines.
Keywords: traditional Chinese medicine Europe development
YANG Xiao, LIU Xuemei
Frontiers of Mechanical Engineering 2007, Volume 2, Issue 1, Pages 57-61 doi: 10.1007/s11465-007-0009-7
Keywords: semi-infinite saturated direction interaction skeleton thermal equilibrium
Neil Stephen LOPEZ, Anthony S.F. CHIU, Jose Bienvenido Manuel BIONA
Frontiers in Energy 2018, Volume 12, Issue 3, Pages 389-399 doi: 10.1007/s11708-018-0578-7
Keywords: transportation LMDI decomposition developing country emissions
Lessons learned from developing and implementing refinery production scheduling technologies
Marcel JOLY, Mario Y. MIYAKE
Frontiers of Engineering Management 2017, Volume 4, Issue 3, Pages 325-337 doi: 10.15302/J-FEM-2017033
Keywords: automation decision making oil refinery optimization production scheduling
Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium
Yan Chen,Wenyan Li,Wen Li,Renjie Chai,Huawei Li
Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 330-335 doi: 10.1007/s11684-016-0459-6
The enhancer of zeste 2 polycomb repressive complex 2 subunit (Ezh2) is a histone-lysine N-methyltransferase enzyme that participates in DNA methylation. Ezh2 has also been reported to play crucial roles in stem cell proliferation and differentiation. However, the detailed expression profile of Ezh2 during mouse cochlear development has not been investigated. Here, we examined the spatiotemporal expression of Ezh2 in the cochlea during embryonic and postnatal development. Ezh2 expression began to be observed in the whole otocyst nuclei at embryonic day 9.5 (E9.5). At E12.5, Ezh2 was expressed in the nuclei of the cochlear prosensory epithelium. At E13.5 and E15.5, Ezh2 was expressed from the apical to the basal turns in the nuclei of the differentiating cochlear epithelium. At postnatal day (P) 0 and 7, the Ezh2 expression was located in the nuclei of the cochlear epithelium in all three turns and could be clearly seen in outer and inner hair cells, supporting cells, the stria vascularis, and spiral ganglion cells. Ezh2 continued to be expressed in the cochlear epithelium of adult mice. Our results provide the basic Ezh2 expression pattern and might be useful for further investigating the detailed role of Ezh2 during cochlear development.
Keywords: polycomb repressive complex Ezh2 expression inner ear cochlea development
Shi SU, Xinxiang YU
Frontiers in Energy 2011, Volume 5, Issue 2, Pages 229-235 doi: 10.1007/s11708-011-0147-9
Keywords: coal mine methane mitigation and utilization lean burn gas turbine catalytic combustion
Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world
Han HAO, Zhexuan MU, Zongwei LIU, Fuquan ZHAO
Frontiers in Energy 2018, Volume 12, Issue 3, Pages 466-480 doi: 10.1007/s11708-018-0561-3
Keywords: hydrogen fuel cell vehicle life cycle assessment energy consumption greenhouse gas (GHG) emissions China
Air quality improvement in Los Angeles—Perspectives for developing cities
David D. Parrish,Jin Xu,Bart Croes,Min Shao
Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 5, doi: 10.1007/s11783-016-0859-5
Keywords: Air pollution Ozone Particulate matter Control technology
Chen Changli
Strategic Study of CAE 2003, Volume 5, Issue 10, Pages 14-19
It is a basic strategy project for developing west China to introduce sea water from Bohai Sea to
Keywords: introducing sea water from Bohai Sea to west China developing west China sandstorm groundwater
Current status and developing trends of the contents of heavy metals in sewage sludges in China
Jun YANG,Mei LEI,Tongbin CHEN,Ding GAO,Guodi ZHENG,Guanghui GUO,Duujong LEE
Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5, Pages 719-728 doi: 10.1007/s11783-013-0600-6
Keywords: sewage sludge heavy metals temporal variation national survey environmental policies
Haiyan Yang, Shangping Xu, Derek E. Chitwood, Yin Wang
Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 5, doi: 10.1007/s11783-020-1254-9
Keywords: Point-of-use water treatment Ceramic water filter Bacterial removal Surface modification Water quality
He LIU, Jianwen YAN, Siwei MENG, Qinghai YANG, Zixiu YAO, Shijia ZHU
Frontiers of Engineering Management 2019, Volume 6, Issue 4, Pages 517-523 doi: 10.1007/s42524-019-0061-0
Keywords: low carbon energy conservation and emission reduction petroleum engineering technology petroleum equipment
Yanshan Petrochemical Company is Developing
Strategic Study of CAE 2000, Volume 2, Issue 1, Pages 92-92
Title Author Date Type Operation
Creation and integration mechanism of instrumentation flexible developing system
Xiaoli XU, Qiushuang LIU
Journal Article
Advances in newly developing therapy for chronic hepatitis C virus infection
Paul J. Pockros
Journal Article
Barriers and countermeasures in developing traditional Chinese medicine in Europe
Yunfang Liu,Zhiping Yang,Jing Cheng,Daiming Fan
Journal Article
Thermally developing forced convection and the corresponding thermal stresses in a porous plate channel
YANG Xiao, LIU Xuemei
Journal Article
of transportation energy consumption and carbon dioxide emissions for the Philippines: the case of developing
Neil Stephen LOPEZ, Anthony S.F. CHIU, Jose Bienvenido Manuel BIONA
Journal Article
Lessons learned from developing and implementing refinery production scheduling technologies
Marcel JOLY, Mario Y. MIYAKE
Journal Article
Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium
Yan Chen,Wenyan Li,Wen Li,Renjie Chai,Huawei Li
Journal Article
Progress in developing an innovative lean burn catalytic turbine technology for fugitive methane mitigation
Shi SU, Xinxiang YU
Journal Article
Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world
Han HAO, Zhexuan MU, Zongwei LIU, Fuquan ZHAO
Journal Article
Air quality improvement in Los Angeles—Perspectives for developing cities
David D. Parrish,Jin Xu,Bart Croes,Min Shao
Journal Article
Introducing Sea Water from Bohai Sea to West China is a Basic Strategy Project for Developing West China
Chen Changli
Journal Article
Current status and developing trends of the contents of heavy metals in sewage sludges in China
Jun YANG,Mei LEI,Tongbin CHEN,Ding GAO,Guodi ZHENG,Guanghui GUO,Duujong LEE
Journal Article
Ceramic water filter for point-of-use water treatment in developing countries: Principles, challenges
Haiyan Yang, Shangping Xu, Derek E. Chitwood, Yin Wang
Journal Article
Practice and understanding of developing new technologies and equipment for green and low-carbon production
He LIU, Jianwen YAN, Siwei MENG, Qinghai YANG, Zixiu YAO, Shijia ZHU
Journal Article